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Article

Association between RAPH1 Gene Haplotypes and CHE2 Locus Phenotypes.

Annals of human genetics - 1 Jul 2016

A De Andrade Fabiana, Batistela Meire S, Amaral Sarah Da C, Dos Santos Willian, Mikami Liya R, Chautard-Freire-Maia Eleidi A, Furtado-Alle Lupe, Souza Ricardo L R

Abstract excerpt

The human butyrylcholinesterase (BChE) is a serum esterase that has been associated with body mass index (BMI) and obesity. Its activity is conditioned by alleles of BCHE gene and the CHE2 locus that codifies an unknown BChE-binding protein (C5 complex). The hypothesis that the CHE2 locus is the RAPH1 gene, which encodes lamellipodin (Lpd), was raised in a study that observed Lpd peptides released from denatured...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 27346732
DOI: 10.1111/ahg.12158

Genes

RAPH1
BCHE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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