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Preemptive Bone Marrow Transplantation and Event-Free Survival in Fanconi Anemia

27 Jun 2016

Abstract excerpt

Fanconi anemia (FA) is a rare inherited bone marrow failure syndrome associated with high risks of severe bone marrow failure (BMF), acute myeloid leukemia (AML), and solid tumors (ST). Bone marrow transplantation (BMT) provides a theoretical cure for hematologic risks (BMF, AML), but it introduces uncertain risks of transplantation-related mortality (TRM) and carcinogenicity. We developed a mathematical (Markov)...

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PMID: 27345141
DOI: 10.1016/j.bbmt.2016.06.018

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