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Fit older adults with advanced myelodysplastic syndromes: who is most likely to benefit from transplant?

Leukemia - 1 Apr 2021

Abel Gregory A, Kim Haesook T, Hantel Andrew, Steensma David P, Stone Richard, Habib Anand, Ho Vincent T, Wadleigh Martha, El-Jawahri Areej, Alyea Edwin P, DeAngelo Daniel J, Koreth John, Antin Joseph H, Soiffer Robert J, Cutler Corey

Abstract excerpt

We conducted a prospective observational study of fit adults aged 60-75 with advanced MDS, enrolled hierarchically for adverse MDS risk (intermediate-2 or high-risk international prognostic score [IPSS], low or intermediate-1 IPSS with poor-risk cytogenetics, or therapy-related MDS) or standard risk with severe cytopenia. A total of 290 patients enrolled at two centers: 175 for adverse risk and 115 for standard...

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Identifiers

PMID: 33204012
DOI: 10.1038/s41375-020-01092-2
PMCID: PMC8035144

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