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Article

Characterization of a new Baeyer-Villiger monooxygenase and conversion to a solely N-or S-oxidizing enzyme by a single R292 mutation.

Biochimica et biophysica acta - 1 Sept 2016

Catucci Gianluca, Zgrablic Ivan, Lanciani Francesco, Valetti Francesca, Minerdi Daniela, Ballou David P, Gilardi Gianfranco, Sadeghi Sheila J

Abstract excerpt

BACKGROUND: Ar-BVMO is a recently discovered Baeyer-Villiger monooxygenase from the genome of Acinetobacter radioresistens S13 closely related to medically relevant ethionamide monooxygenase EtaA (prodrug activator) and capable of inactivating the imipenem antibiotic. METHODS: The co-substrate preference as well as steady-state and rapid kinetics studies of the recombinant purified protein were carried out using...

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PMID: 27344049
DOI: 10.1016/j.bbapap.2016.06.010

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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