Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

DMD genotypes and loss of ambulation in the CINRG Duchenne Natural History Study.

Neurology - 26 Jul 2016

Bello Luca, Morgenroth Lauren P, Gordish-Dressman Heather, Hoffman Eric P, McDonald Craig M, Cirak Sebahattin

Abstract excerpt

OBJECTIVE: To correlate time to loss of ambulation (LoA) and different truncating DMD gene mutations in a large, prospective natural history study of Duchenne muscular dystrophy (DMD), with particular attention to mutations amenable to emerging molecular treatments. METHODS: We analyzed data from the Cooperative International Neuromuscular Research Group Duchenne Natural History Study for participants with DMD...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Codon
Share to Codon, Nonsense
Share to Dystrophin

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gait Disorders, Neurologic

Share to Gene Duplication

Share to Glucocorticoids

Share to Kaplan-Meier Estimate

Share to Muscular Dystrophy, Duchenne

Source

Open in PubMed Open full text

Identifiers

PMID: 27343068
DOI: 10.1212/WNL.0000000000002891
PMCID: PMC4977110

Genes

DMD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

DMD genotypes and loss of ambulation in the CINRG Duchenne Natural History Study.PMID 27343068Read ↗

Genotype characterization and delayed loss of ambulation by glucocorticoids in a large cohort of patients with Duchenne muscular dystrophy.Semantic proximity Read ↗

The impact of genotype on age at loss of ambulation in individuals with Duchenne muscular dystrophy treated with corticosteroids: A single-center study of 555 patients.Semantic proximity Read ↗

The CINRG Becker Natural History Study: Baseline characteristics.Semantic proximity Read ↗

DMD Genotypes and Motor Function in Duchenne Muscular Dystrophy: A Multi-institution Meta-analysis With Implications for Clinical Trials.Semantic proximity Read ↗

The NorthStar Ambulatory Assessment in Duchenne muscular dystrophy: considerations for the design of clinical trials.Semantic proximity Read ↗

DMD genotype correlations from the Duchenne Registry: Endogenous exon skipping is a factor in prolonged ambulation for individuals with a defined mutation subtype.Semantic proximity Read ↗

Genetic Modifiers of Duchenne Muscular Dystrophy and Dilated Cardiomyopathy.Semantic proximity Read ↗

The impact of genotype on outcomes in individuals with Duchenne muscular dystrophy: A systematic review.Semantic proximity Read ↗

Findings from the Longitudinal CINRG Becker Natural History Study.Semantic proximity Read ↗

A genome-wide association analysis of loss of ambulation in dystrophinopathy patients suggests multiple candidate modifiers of disease severitySemantic proximity Read ↗

Longitudinal motor function in proximal versus distal DMD pathogenic variants.Semantic proximity Read ↗

Diversity of Dystrophin Gene Mutations and Disease Progression in a Contemporary Cohort of Duchenne Muscular Dystrophy.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.