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Article

The impact of genotype on outcomes in individuals with Duchenne muscular dystrophy: A systematic review.

Muscle & nerve - 1 Mar 2022

Szabo Shelagh M, Gooch Katherine L, Mickle Alexis T, Salhany Renna M, Connolly Anne M

Abstract excerpt

Duchenne muscular dystrophy (DMD) is associated with progressive muscle weakness, loss of ambulation (LOA), and early mortality. In this review we have synthesized published data on the clinical course of DMD by genotype. Using a systematic search implemented in Medline and Embase, 53 articles were identified that describe the clinical course of DMD, with pathogenic variants categorizable by exon skip or...

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Identifiers

PMID: 34878187
DOI: 10.1002/mus.27463

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