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Vascular endothelial growth factor (VEGF) +405 C/G polymorphism is associated with essential hypertension in a population from Tehran of Iran.

Molecular biology reports - 1 May 2012

Hamedian Amir Abbas, Esteghamati Alireza, Noshad Sina, Mozafari Mohammad, Moin-Tavakkoli Hosein, Nakhjavani Manouchehr, Mahmoudi Touraj, Nikzamir Mahfam, Safary Reza, Nikzamir Abdolrahim

Abstract excerpt

Vascular endothelial growth factor (VEGF) has long been recognized as a hypotensive mediator. Little is known regarding the contribution of polymorphisms in VEGF gene to essential hypertension (EH), however. We aimed to investigate the association between +405 VEGF C/G single nucleotide polymorphism (SNP) and occurrence of EH in a sample of patients with diabetes. A study population of 474 subjects with diabetes...

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PMID: 22209952
DOI: 10.1007/s11033-011-1440-8

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