Article
Circulating immune cell phenotype can predict the outcome of lenalidomide plus low-dose dexamethasone treatment in patients with refractory/relapsed multiple myeloma.
Cancer immunology, immunotherapy : CII - 1 Aug 2016
Lee Sung-Eun, Lim Ji-Young, Ryu Da-Bin, Kim Tae Woo, Yoon Jae-Ho, Cho Byung-Sik, Eom Ki-Seong, Kim Yoo-Jin, Kim Hee-Je, Lee Seok, Cho Seok-Goo, Kim Dong-Wook, Lee Jong-Wook, Min Woo-Sung, Kim Myungshin, Min Chang-Ki
Abstract excerpt
Although the antimyeloma effect of lenalidomide is associated with activation of the immune system, the exact in vivo immunomodulatory mechanisms of lenalidomide combined with low-dose dexamethasone (Len-dex) in refractory/relapsed multiple myeloma (RRMM) patients remain unclear. In this study, we analyzed the association between immune cell populations and clinical outcomes in patients receiving Len-dex for the...
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