Article
Inter-Laboratory Evaluation of a Next-Generation Sequencing Panel for Acute Myeloid Leukemia.
Molecular diagnosis & therapy - 1 Oct 2016
Haslam Karl, Catherwood Mark A, Dobbin Edwina, Sproul Anne, Langabeer Stephen E, Mills Ken I
Abstract excerpt
INTRODUCTION: Acute myeloid leukemia (AML) is a heterogeneous clonal disorder often associated with dismal overall survival. The clinical diversity of AML is reflected in the range of recurrent somatic mutations in several genes, many of which have a prognostic and therapeutic value. Targeted next-generation sequencing (NGS) of these genes has the potential for translation into clinical practice. In order to...
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