High stability of faecal microbiome composition in guanidine thiocyanate solution at room temperature and robustness during colonoscopy

Abstract excerpt

We read with interest the paper by Jalanka et al ,1 who examined the influence of bowel preparation on intestinal microbiota by using phylogenetic microarray and quantitative PCR analyses of frozen samples. Conventionally, faecal samples are frozen on dry ice or in a deep-freezer (at −80°C) immediately after collection, as done by Jalanka et al , because bacterial taxa can change appreciably within 15 min at room...

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