Impact that Timing of Genetic Mutation Diagnosis has on Surgical Decision Making and Outcome for BRCA1/BRCA2 Mutation Carriers with Breast Cancer.

doi:10.1245/s10434-016-5328-7

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Article

Impact that Timing of Genetic Mutation Diagnosis has on Surgical Decision Making and Outcome for BRCA1/BRCA2 Mutation Carriers with Breast Cancer.

Annals of surgical oncology - 1 Oct 2016

Chiba Akiko, Hoskin Tanya L, Hallberg Emily J, Cogswell Jodie A, Heins Courtney N, Couch Fergus J, Boughey Judy C

Abstract excerpt

BACKGROUND: Deleterious BRCA mutation carriers with breast cancer are at increased risk for additional breast cancer events. This study evaluated the impact that timing of identification of BRCA+ status has on surgical decision and outcome. METHODS: The authors reviewed all BRCA carriers at their institution whose breast cancer was diagnosed between January 1996 and June 2015. Patient surveys, medical records,...

Topics

Adult
Aged
Decision Making
Female
Genes, BRCA1
Genes, BRCA2
Genetic Testing
Heterozygote
Humans
Kaplan-Meier Estimate
Mastectomy, Segmental

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Middle Aged

Mutation

Neoplasm Staging

Prophylactic Mastectomy

Time Factors

Unilateral Breast Neoplasms

Young Adult

Source

Open in PubMed Open full text

Identifiers

PMID: 27338744
DOI: 10.1245/s10434-016-5328-7
PMCID: PMC5113286

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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Impact that Timing of Genetic Mutation Diagnosis has on Surgical Decision Making and Outcome for BRCA1/BRCA2 Mutation Carriers with Breast Cancer.PMID 27338744Read ↗

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