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Article

Development and Application of a Simple Plaque Assay for the Human Malaria Parasite Plasmodium falciparum.

PloS one - 1 Jan 2016

Thomas James A, Collins Christine R, Das Sujaan, Hackett Fiona, Graindorge Arnault, Bell Donald, Deu Edgar, Blackman Michael J

Abstract excerpt

Malaria is caused by an obligate intracellular protozoan parasite that replicates within and destroys erythrocytes. Asexual blood stages of the causative agent of the most virulent form of human malaria, Plasmodium falciparum, can be cultivated indefinitely in vitro in human erythrocytes, facilitating experimental analysis of parasite cell biology, biochemistry and genetics. However, efforts to improve...

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Identifiers

PMID: 27332706
DOI: 10.1371/journal.pone.0157873
PMCID: PMC4917082

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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