Article
Mutation in West Nile Virus Structural Protein prM during Human Infection.
Emerging infectious diseases - 1 Sept 2016
Lustig Yaniv, Lanciotti Robert S, Hindiyeh Musa, Keller Nathan, Milo Ron, Mayan Shlomo, Mendelson Ella
Abstract excerpt
A mutation leading to substitution of a key amino acid in the prM protein of West Nile virus (WNV) occurred during persistent infection of an immunocompetent patient. WNV RNA persisted in the patient's urine and serum in the presence of low-level neutralizing antibodies. This case demonstrates active replication of WNV during persistent infection.
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