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Article

Autophagy regulates spermatid differentiation via degradation of PDLIM1

16 Jun 2016

Abstract excerpt

Spermiogenesis is a complex and highly ordered spermatid differentiation process that requires reorganization of cellular structures. We have previously found that Atg7 is required for acrosome biogenesis. Here, we show that autophagy regulates the round and elongating spermatids. Specifically, we found that Atg7 is required for spermatozoa flagella biogenesis and cytoplasm removal during spermiogenesis....

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PMID: 27310465
DOI: 10.1080/15548627.2016.1192750

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