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Article

Role of hypoxia and vascular endothelial growth factors in lymphangiogenesis

1 Jan 2014

Abstract excerpt

Hypoxia is a major condition for the induction of angiogenesis during tumor development but its role in lymphangiogenesis remains unclear. Blood and lymphatic vasculatures are stimulated by growth factors from the vascular endothelial family: the VEGFs. In this review, we investigate the role of hypoxia in the molecular regulation of synthesis of lymphangiogenic growth factors VEGF-A, VEGF-C, and VEGF-D. Gene...

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Share to Angiogenesis and VEGF in Cancer
Share to Cancer, Hypoxia, and Metabolism
Share to Lymphatic System and Diseases

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Identifiers

PMID: 27308316
DOI: 10.4161/mco.29907

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