Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Ecophysiological consequences of alcoholism on human gut microbiota: implications for ethanol-related pathogenesis of colon cancer.

Scientific reports - 13 Jun 2016

Tsuruya Atsuki, Kuwahara Akika, Saito Yuta, Yamaguchi Haruhiko, Tsubo Takahisa, Suga Shogo, Inai Makoto, Aoki Yuichi, Takahashi Seiji, Tsutsumi Eri, Suwa Yoshihide, Morita Hidetoshi, Kinoshita Kenji, Totsuka Yukari, Suda Wataru, Oshima Kenshiro, Hattori Masahira, Mizukami Takeshi, Yokoyama Akira, Shimoyama Takefumi, Nakayama Toru

Abstract excerpt

Chronic consumption of excess ethanol increases the risk of colorectal cancer. The pathogenesis of ethanol-related colorectal cancer (ER-CRC) is thought to be partly mediated by gut microbes. Specifically, bacteria in the colon and rectum convert ethanol to acetaldehyde (AcH), which is carcinogenic. However, the effects of chronic ethanol consumption on the human gut microbiome are poorly understood, and the role...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acetaldehyde
Share to Alcohol Dehydrogenase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Alcoholism

Share to Aldehyde Dehydrogenase, Mitochondrial

Share to Bacteroides

Share to Ethanol

Share to Gastrointestinal Microbiome

Share to Streptococcus

Source

Open in PubMed Open full text

Identifiers

PMID: 27295340
DOI: 10.1038/srep27923
PMCID: PMC4904738

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Ecophysiological consequences of alcoholism on human gut microbiota: implications for ethanol-related pathogenesis of colon cancer.PMID 27295340Read ↗

Host-Microbiome Interactions in Alcoholic Liver DiseaseSemantic proximity Read ↗

Role of gut bacterial and non-bacterial microbiota in alcohol-associated liver disease: Molecular mechanisms, biomarkers, and therapeutic prospectiveSemantic proximity Read ↗

Local Acetaldehyde—An Essential Role in Alcohol-Related Upper Gastrointestinal Tract CarcinogenesisSemantic proximity Read ↗

Acetaldehyde, Microbes, and Cancer of the Digestive TractSemantic proximity Read ↗

Molecular Mechanisms of Alcohol-Induced Colorectal CarcinogenesisSemantic proximity Read ↗

Concurrent gut transcriptome and microbiota profiling following chronic ethanol consumption in nonhuman primatesSemantic proximity Read ↗

Alcohol exposure alters the diversity and composition of oral microbiomeSemantic proximity Read ↗

Alterations and correlations of gut microbiota, fecal, and serum metabolome characteristics in a rat model of alcohol use disorderSemantic proximity Read ↗

Ethanolamine improves colonic barrier functions and inflammatory immunoreactions via shifting microbiome dysbiosisSemantic proximity Read ↗

Direct effects of alcohol on gut‐epithelial barrier: Unraveling the disruption of physical and chemical barrier of the gut‐epithelial barrier that compromises the host–microbiota interface upon alcohol exposureSemantic proximity Read ↗

Gut non-bacterial microbiota contributing to alcohol-associated liver diseaseSemantic proximity Read ↗

Metagenomic analyses of alcohol induced pathogenic alterations in the intestinal microbiome and the effect of Lactobacillus rhamnosus GG treatment.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.