Direct effects of alcohol on gut‐epithelial barrier: Unraveling the disruption of physical and chemical barrier of the gut‐epithelial barrier that compromises the host–microbiota interface upon alcohol exposure

Abstract excerpt

The development of alcohol-associated diseases is multifactorial, mechanism of which involves metabolic alteration, dysregulated immune response, and a perturbed intestinal host-environment interface. Emerging evidence has pinpointed the critical role of the intestinal host-microbiota interaction in alcohol-induced injuries, suggesting its contribution to disease initiation and development. To maintain...

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