Article
Combined role of vitamin D status and CYP24A1 in the transition to systemic lupus erythematosus.
Annals of the rheumatic diseases - 1 Jan 2017
Young Kendra A, Munroe Melissa E, Guthridge Joel M, Kamen Diane L, Niewold Timothy B, Gilkeson Gary S, Weisman Michael H, Ishimori Mariko L, Kelly Jennifer, Gaffney Patrick M, Sivils Kathy H, Lu Rufei, Wallace Daniel J, Karp David R, Harley John B, James Judith A, Norris Jill M
Abstract excerpt
OBJECTIVE: We examined whether measures of vitamin D were associated with transitioning to systemic lupus erythematosus (SLE) in individuals at risk for SLE. METHODS: 436 individuals who reported having a relative with SLE but who did not have SLE themselves were evaluated at baseline and again an average of 6.3 (±3.9) years later. Fifty-six individuals transitioned to SLE (≥4 cumulative American College of...
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