Article
Up-regulation of Plasma Hexosylceramide (d18: 1/18: 1) Contributes to Genotype 2 Virus Replication in Chronic Hepatitis C: A 20-Year Cohort Study.
Medicine - 1 Jun 2016
Zhang Jin-Yan, Qu Feng, Li Jun-Feng, Liu Mei, Ren Feng, Zhang Jing-Yun, Bian Dan-Dan, Chen Yu, Duan Zhong-Ping, Zhang Jin-Lan, Zheng Su-Jun
Abstract excerpt
The aim of the present study was to explore the relationship between plasma sphingolipids and hepatitis C virus (HCV) replication in chronic hepatitis C (CHC) patients.A cohort of 120 treatment-naïve CHC patients was included. Liver biopsies and the Scheuer scoring system were used to assess hepatic inflammatory activity. Blood biochemical indicators, HCV-RNA load, and immunological markers were also measured....
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