Article
Accounting for reciprocal host-microbiome interactions in experimental science.
Nature - 9 Jun 2016
Stappenbeck Thaddeus S, Virgin Herbert W
Abstract excerpt
Mammals are defined by their metagenome, a combination of host and microbiome genes. This knowledge presents opportunities to further basic biology with translation to human diseases. However, the now-documented influence of the metagenome on experimental results and the reproducibility of in vivo mammalian models present new challenges. Here we provide the scientific basis for calling on all investigators,...
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