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Article

MicroRNA-17 induces epithelial-mesenchymal transition consistent with the cancer stem cell phenotype by regulating CYP7B1 expression in colon cancer.

International journal of molecular medicine - 1 Aug 2016

Xi Xiang-Peng, Zhuang Jing, Teng Mu-Jian, Xia Li-Jian, Yang Ming-Yu, Liu Qing-Gen, Chen Jing-Bo

Abstract excerpt

MicroRNA-17 (miRNA-17/miR‑17) expression has been confirmed to be significantly higher in colorectal cancer tissues than in normal tissues. However, its exact role in colorectal cancer has not yet been fully elucidated. In this study, we found that miR-17 not only promoted epithelial-mesenchymal transition (EMT), but also promoted the formation of a stem cell-like population in colon cancer DLD1 cells. We also...

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Identifiers

PMID: 27278684
DOI: 10.3892/ijmm.2016.2624

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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