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Article

Genetic alterations of differentiated thyroid carcinoma in iodine-rich and iodine-deficient countries.

Cancer medicine - 1 Aug 2016

Vuong Huy Gia, Kondo Tetsuo, Oishi Naoki, Nakazawa Tadao, Mochizuki Kunio, Inoue Tomohiro, Tahara Ippei, Kasai Kazunari, Hirokawa Mitsuyoshi, Tran Thong Minh, Katoh Ryohei

Abstract excerpt

BRAF V600E mutation, RET rearrangements, and RAS mutations are the common genetic alterations in differentiated thyroid carcinomas derived from follicular thyroid cells. However, the relationship between these alterations and iodine intake is still controversial. To clarify the influence of iodine intake on the occurrence of differentiated thyroid carcinomas, we performed molecular analyses for two differentiated...

Topics

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Carcinoma, Papillary
Gene Rearrangement
Iodine
Oncogene Proteins, Fusion
Protein-Tyrosine Kinases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Thyroid Cancer, Papillary

Thyroid Neoplasms

Source

Open in PubMed Open full text

Identifiers

PMID: 27264674
DOI: 10.1002/cam4.781
PMCID: PMC4898973

Genes

RET
BRAF
NRAS
HRAS
KRAS

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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