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MicroRNA-655-3p functions as a tumor suppressor by regulating ADAM10 and β-catenin pathway in Hepatocellular Carcinoma

4 Jun 2016

Abstract excerpt

BACKGROUND: Increasing evidence suggests that microRNAs (miRNAs) play critical roles in malignant transformation, tumor progression and metastasis. Aberrant miR-655-3p expression has been associated with several cancers. However, the role and underlying mechanism of miR-655-3p in the development of hepatocellular carcinoma (HCC) remains unclear. METHODS: MiR-655-3p expression was detected by quantitative RT-PCR...

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PMID: 27259866
DOI: 10.1186/s13046-016-0368-1

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