Development and clinical application of an integrative genomic approach to personalized cancer therapy.

doi:10.1186/s13073-016-0313-0

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Development and clinical application of an integrative genomic approach to personalized cancer therapy.

Genome medicine - 1 Jun 2016

Uzilov Andrew V, Ding Wei, Fink Marc Y, Antipin Yevgeniy, Brohl Andrew S, Davis Claire, Lau Chun Yee, Pandya Chetanya, Shah Hardik, Kasai Yumi, Powell James, Micchelli Mark, Castellanos Rafael, Zhang Zhongyang, Linderman Michael, Kinoshita Yayoi, Zweig Micol, Raustad Katie, Cheung Kakit, Castillo Diane, Wooten Melissa, Bourzgui Imane, Newman Leah C, Deikus Gintaras, Mathew Bino, Zhu Jun, Glicksberg Benjamin S, Moe Aye S, Liao Jun, Edelmann Lisa, Dudley Joel T, Maki Robert G, Kasarskis Andrew, Holcombe Randall F, Mahajan Milind, Hao Ke, Reva Boris, Longtine Janina, Starcevic Daniela, Sebra Robert, Donovan Michael J, Li Shuyu, Schadt Eric E, Chen Rong

Abstract excerpt

BACKGROUND: Personalized therapy provides the best outcome of cancer care and its implementation in the clinic has been greatly facilitated by recent convergence of enormous progress in basic cancer research, rapid advancement of new tumor profiling technologies, and an expanding compendium of targeted cancer therapeutics. METHODS: We developed a personalized cancer therapy (PCT) program in a clinical setting,...

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PMID: 27245685
DOI: 10.1186/s13073-016-0313-0
PMCID: PMC4888213

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

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