Article
Laboratory Assays in Evaluation of Lynch Syndrome in Patients with Endometrial Carcinoma.
Surgical pathology clinics - 1 Jun 2016
Djordjevic Bojana, Broaddus Russell R
Abstract excerpt
This article reviews the main tissue testing modalities for Lynch Syndrome in the pathology laboratory, such as immunohistochemistry and PCR based analyses, and discusses their routine application, interpretation pitfalls, and troubleshooting of common technical performance issues. Discrepancies between laboratory and genetic testing may arise, and are examined in the context of the complexity of molecular...
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