Article
Ovarian Cancer in Hereditary Cancer Susceptibility Syndromes.
Surgical pathology clinics - 1 Jun 2016
Nakonechny Quentin B, Gilks C Blake
Abstract excerpt
Hereditary breast and ovarian cancer (HBOC) syndrome and Lynch syndrome (LS) are associated with increased risk of developing ovarian carcinoma. Patients with HBOC have a lifetime risk of up to 50% of developing high-grade serous carcinoma of tube or ovary; patients with LS have a 10% lifetime risk of developing endometrioid or clear cell carcinoma of the ovary. Testing all patients with tubo-ovarian high-grade...
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