Article
Alveolar epithelial disintegrity in pulmonary fibrosis.
American journal of physiology. Lung cellular and molecular physiology - 1 Aug 2016
Kulkarni Tejaswini, de Andrade Joao, Zhou Yong, Luckhardt Tracy, Thannickal Victor J
Abstract excerpt
Idiopathic pulmonary fibrosis (IPF) is a chronic lung disease characterized by progressive decline in lung function, resulting in significant morbidity and mortality. Current concepts of the pathogenesis of IPF primarily center on dysregulated epithelial cell repair and altered epithelial-mesenchymal communication and extracellular matrix deposition following chronic exposure to cigarette smoke or environmental...
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