Article
Hfq-dependent alterations of the transcriptome profile and effects on quorum sensing in Pseudomonas aeruginosa.
Molecular microbiology - 1 Mar 2006
Sonnleitner Elisabeth, Schuster Martin, Sorger-Domenigg Theresa, Greenberg Everett Peter, Bläsi Udo
Abstract excerpt
The Pseudomonas aeruginosa quorum-sensing (QS) systems, Las and Rhl, control the production of several virulence factors and other proteins, which are important to sustain adverse conditions. A comparative transcriptome analysis of a rpoS (-) and a rpoS(-)hfq( -) strain indicated that the Sm-like RNA-binding protein Hfq affects approximately 5% of the P. aeruginosa O1 transcripts. Among these transcripts 72 were...
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