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Article

Negative pressure induces p120-catenin-dependent adherens junction disassembly in keratinocytes during wound healing.

Biochimica et biophysica acta - 1 Sept 2016

Huang Ching-Hui, Hsu Chih-Chin, Chen Carl Pai-Chu, Chow Shu-Er, Wang Jong-Shyan, Shyu Yu-Chiau, Lu Mu-Jie

Abstract excerpt

A negative-pressure of 125mmHg (NP) has been widely used to treat chronic wounds in modern medicine. Keratinocytes under NP treatment have shown accelerated cell movement and decreased E-cadherin expression. However, the molecular mechanism of E-cadherin regulation under NP remains incompletely understood. Therefore, we investigated the E-cadherin regulation in keratinocytes (HaCaT cells) under NP. HaCaT cells...

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Identifiers

PMID: 27220534
DOI: 10.1016/j.bbamcr.2016.05.017

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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