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Validation of break-apart and fusion MYC probes using a digital fluorescence in situhybridization capture and imaging system

1 Jan 2016

Abstract excerpt

INTRODUCTION: Detection of MYC translocations using fluorescence in situ hybridization (FISH) is important in the evaluation of lymphomas, in particular, Burkitt lymphoma and diffuse large B-cell lymphoma. Our aim was to validate a digital FISH capture and imaging system for the detection of MYC 8q24 translocations using LSI-MYC (a break-apart probe) and MYC 8;14 translocation using IGH-MYC (a fusion probe)....

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PMID: 27217970
DOI: 10.4103/2153-3539.181764

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