Article
HtrA Is Important for Stress Resistance and Virulence in Haemophilus parasuis.
Infection and immunity - 1 Aug 2016
Zhang Luhua, Li Ying, Wen Yiping, Lau Gee W, Huang Xiaobo, Wu Rui, Yan Qigui, Huang Yong, Zhao Qin, Ma Xiaoping, Wen Xintian, Cao Sanjie
Abstract excerpt
Haemophilus parasuis is an opportunistic pathogen that causes Glässer's disease in swine, with polyserositis, meningitis, and arthritis. The high-temperature requirement A (HtrA)-like protease, which is involved in protein quality control, has been reported to be a virulence factor in many pathogens. In this study, we showed that HtrA of H. parasuis (HpHtrA) exhibited both chaperone and protease activities....
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