Article
Lactase Non-Persistence Genotyping: Comparison of Two Real-Time PCR Assays and Assessment of Concomitant Fructose/Sorbitol Malabsorption Rates.
Clinical laboratory - 1 Jan 2016
Enko Dietmar, Pollheimer Verena, Németh Stefan, Pühringer Helene, Stolba Robert, Halwachs-Baumann Gabriele, Kriegshäuser Gernot
Abstract excerpt
BACKGROUND: Genetic testing is a standard technique for the diagnosis of primary adult-type hypolactasia, also referred to as lactase non-persistence. The aim of this study was to compare the lactase gene (LCT) C/T-13910 polymorphism genotyping results of two commercially available real-time (RT)-PCR assays in patients referred to our outpatient clinic for primary lactose malabsorption testing. Furthermore,...
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