Article
Adenomas as a risk factor in familial colorectal cancer: implications for screening and surveillance in the UK.
Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland - 1 Sept 2016
Buczacki S J A, Wheeler J M D
Abstract excerpt
Colorectal cancer (CRC) develops from normal epithelium, through dysplastic adenoma to invasive carcinoma. In addition to familial adenomatous polyposis and Lynch syndrome, approximately 10-35% of CRCs are familial in nature. CRC screening and surveillance programmes are based on an understanding of the natural history of polyps and rely on the ability to remove premalignant lesions endoscopically before they are...
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