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Article

Cross-Disease Transcriptomics: Unique IL-17A Signaling in Psoriasis Lesions and an Autoimmune PBMC Signature.

The Journal of investigative dermatology - 1 Sept 2016

Swindell William R, Sarkar Mrinal K, Liang Yun, Xing Xianying, Gudjonsson Johann E

Abstract excerpt

Transcriptome studies of psoriasis have identified robust changes in mRNA expression through large-scale analysis of patient cohorts. These studies, however, have analyzed all mRNA changes in aggregate, without distinguishing between disease-specific and nonspecific differentially expressed genes (DEGs). In this study, RNA-seq meta-analysis was used to identify (1) psoriasis-specific DEGs altered in few diseases...

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Identifiers

PMID: 27206706
DOI: 10.1016/j.jid.2016.04.035
PMCID: PMC5234565

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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