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Article

No association between dysplasminogenemia with p.Ala620Thr mutation and atypical hemolytic uremic syndrome.

International journal of hematology - 1 Aug 2016

Miyata Toshiyuki, Uchida Yumiko, Yoshida Yoko, Kato Hideki, Matsumoto Masanori, Kokame Koichi, Fujimura Yoshihiro, Nangaku Masaomi

Abstract excerpt

Atypical hemolytic uremic syndrome (aHUS), a form of thrombotic microangiopathy, is caused by the uncontrolled activation of the alternative pathway of complement on the cell surface that leads to microangiopathic hemolytic anemia, thrombocytopenia, and renal failure. A recent genetic analysis of aHUS patients identified deleterious mutations not only in complement or complement regulatory genes but also in the...

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PMID: 27194432
DOI: 10.1007/s12185-016-2021-3

Genes

MAF
PLG

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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