Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Abnormal Epigenetic Modifications in Peripheral T Cells from Patients with Abdominal Aortic Aneurysm Are Correlated with Disease Development.

Journal of vascular research - 1 Jan 2015

Jiang Han, Xia Qian, Xin Shijie, Lun Yun, Song Jianbo, Tang Dianjun, Liu Xun, Ren Jiancong, Duan Zhiquan, Zhang Jian

Abstract excerpt

BACKGROUND: Increasing evidence suggests that abdominal aortic aneurysm (AAA) is a T-cell-mediated autoimmune condition. This study investigates the epigenetic modifications that occur in the T cells of AAA patients and evaluates the correlation of these modifications with disease development. METHODS AND RESULTS: Peripheral T cells were collected from 101 AAA patients and 102 healthy controls (HCs). DNA...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acetylation
Share to Aortic Aneurysm, Abdominal

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Autoimmunity

Share to CpG Islands

Share to DNA (Cytosine-5-)-Methyltransferase 1

Share to DNA (Cytosine-5-)-Methyltransferases

Share to Histone Deacetylases

Share to Histones

Source

Identifiers

PMID: 27194055
DOI: 10.1159/000445771

Genes

DNMT1
HDAC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Abnormal Epigenetic Modifications in Peripheral T Cells from Patients with Abdominal Aortic Aneurysm Are Correlated with Disease Development.PMID 27194055Read ↗

Genetic and epigenetic mechanisms and their possible role in abdominal aortic aneurysm.Semantic proximity Read ↗

The Role of Epigenetic Modifications in Abdominal Aortic Aneurysm PathogenesisSemantic proximity Read ↗

Epigenetic Biomarkers in Thoracic Aortic Aneurysm, Dissection, and Bicuspid Aortopathy: A Comprehensive ReviewSemantic proximity Read ↗

Histone acetylation and histone acetyltransferases show significant alterations in human abdominal aortic aneurysmSemantic proximity Read ↗

The potential role of DNA methylation in the pathogenesis of abdominal aortic aneurysm.Semantic proximity Read ↗

The Potential Role of DNA Methylation in Abdominal Aortic AneurysmsSemantic proximity Read ↗

Epigenetics in Abdominal Aortic Aneurysm: Mechanisms and Risk PredictionSemantic proximity Read ↗

SMYD2 promoter DNA methylation is associated with abdominal aortic aneurysm (AAA) and SMYD2 expression in vascular smooth muscle cellsSemantic proximity Read ↗

The Role of Epigenetics in Brain Aneurysm and Subarachnoid Hemorrhage: A Comprehensive ReviewSemantic proximity Read ↗

Circulatory CD4-Positive T-Lymphocyte Imbalance Mediated by Homocysteine-Induced AIM2 and NLRP1 Inflammasome Upregulation and Activation Is Associated with Human Abdominal Aortic Aneurysm.Semantic proximity Read ↗

Bioinformatic analyses of the role of m6A RNA methylation regulators in abdominal aortic aneurysmSemantic proximity Read ↗

Genetic and epigenetic regulation of abdominal aortic aneurysms.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.