Article
Protein Interacting with Never in Mitosis A-1 Induces Glutamatergic and GABAergic Neuronal Differentiation in Human Dental Pulp Stem Cells.
Journal of endodontics - 1 Jul 2016
Cho Young-Ah, Kim Duck-Su, Song Miyeoun, Bae Won-Jung, Lee Soojung, Kim Eun-Cheol
Abstract excerpt
INTRODUCTION: The purpose of this study was to investigate the role of protein interacting with never in mitosis A-1 (PIN1) in the neuronal or glial differentiation of human dental pulp stem cells (hDPSCs) and whether PIN1 can regulate determination of neuronal sub-phenotype. METHODS: After magnetic-activated cell sorting to separate CD34(+)/c-kit(+)/STRO-1(+) hDPSCs, cells were cultured in neurogenic medium....
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