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Article

LL37:DNA complexes provide antimicrobial activity against intracellular bacteria in human macrophages

14 May 2016

Abstract excerpt

As part of the innate host response neutrophils release neutrophil extracellular traps (NETs), protein:DNA complexes that contain a number of antimicrobial peptides (AMPs), such as cathelicidin. Human cathelicidin in its active form, LL37, has potent antimicrobial activity against bacteria. However, whether LL37 derived from NETs contributes to antimicrobial activity against intracellular pathogens remains...

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PMID: 27177697
DOI: 10.1111/imm.12620

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