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Analysis of the genetic association between IL27 variants and coronary artery disease in a Chinese Han population.

Scientific reports - 12 May 2016

Fan Qian, Nie Shaofang, Li Sihui, Liao Yuhua, Zhang Hongsong, Zha Lingfeng, Wang Fan, Tang Tingting, Xia Ni, Xu Chengqi, Wang Pengyun, Xie Tian, Xie Jiangjiao, Lu Qiulun, Li Qingxian, Qian Jin, Li Bin, Wu Gang, Wu Yanxia, Yang Yan, Wang Qing K, Tu Xin, Cheng Xiang

Abstract excerpt

Interleukin-27 (IL-27) is an important cytokine in inflammatory diseases, including coronary artery disease (CAD). To explore the precise role of IL-27 in CAD, we investigated the genetic association between IL27 and CAD in the GeneID Chinese Han population. A two-stage case control association analysis was performed for 3075 CAD cases and 2802 controls. Logistic regression analysis was used to adjust the...

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Identifiers

PMID: 27174010
DOI: 10.1038/srep25782
PMCID: PMC4865940

Genes

CAD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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