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Article

Self-resistance in Streptomyces, with Special Reference to β-Lactam Antibiotics

10 May 2016

Abstract excerpt

Antibiotic resistance is one of the most serious public health problems. Among bacterial resistance, β-lactam antibiotic resistance is the most prevailing and threatening area. Antibiotic resistance is thought to originate in antibiotic-producing bacteria such as Streptomyces. In this review, β-lactamases and penicillin-binding proteins (PBPs) in Streptomyces are explored mainly by phylogenetic analyses from the...

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PMID: 27171072
DOI: 10.3390/molecules21050605

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