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Article

Treatment options for chronic mucocutaneous candidiasis.

The Journal of infection - 5 Jul 2016

van de Veerdonk Frank L, Netea Mihai G

Abstract excerpt

Autosomal dominant chronic mucocutaneous candidiasis (AD-CMC) is a rare and severe primary immunodeficiency that is characterized by mucocutaneous fungal infection, autoimmunity, cerebral aneurysms, and oropharyngeal and esophageal cancer. Recently, it was discovered that STAT1 mutations are responsible for AD-CMC. These mutations lead to the inability of STAT1 to be dephosphorylated, resulting in...

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Share to Candidiasis, Chronic Mucocutaneous
Share to STAT1 gene
Share to Immunologic Deficiency Syndromes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Signal Transduction

Share to STAT1 Transcription Factor

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Source

Identifiers

PMID: 27161991
DOI: 10.1016/j.jinf.2016.04.023

Genes

STAT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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