Article
Two Elderly Patients with Philadelphia Chromosome Positive Mixed Phenotype Acute Leukemia Who Were Successfully Treated with Dasatinib and Prednisolone.
Internal medicine (Tokyo, Japan) - 1 Jan 2016
Takata Hiroyuki, Ikebe Taichi, Sasaki Hitohiro, Miyazaki Yasuhiko, Ohtsuka Eiichi, Saburi Yoshio, Ogata Masao, Shirao Kuniaki
Abstract excerpt
Philadelphia chromosome positive (Ph+) mixed phenotype acute leukemia (MPAL) is a rare type of acute leukemia having both myeloid and lymphoid features for which no optimal treatment has yet been established. We herein describe two elderly Ph+MPAL patients who achieved molecular remission without any serious adverse events by treatment with dasatinib and prednisolone. Although dasatinib induction therapy combined...
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