Article
Chronic myeloid leukemia: reminiscences and dreams.
Haematologica - 1 May 2016
Mughal Tariq I, Radich Jerald P, Deininger Michael W, Apperley Jane F, Hughes Timothy P, Harrison Christine J, Gambacorti-Passerini Carlo, Saglio Giuseppe, Cortes Jorge, Daley George Q
Abstract excerpt
With the deaths of Janet Rowley and John Goldman in December 2013, the world lost two pioneers in the field of chronic myeloid leukemia. In 1973, Janet Rowley, unraveled the cytogenetic anatomy of the Philadelphia chromosome, which subsequently led to the identification of the BCR-ABL1 fusion gene and its principal pathogenetic role in the development of chronic myeloid leukemia. This work was also of major...
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