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Article

A long non-coding RNA,<i>APOA4</i>-AS, regulates<i>APOA4</i>expression depending on HuR in mice

29 Apr 2016

Abstract excerpt

Long non-coding RNAs (lncRNAs) have been shown to be critical biomarkers or therapeutic targets for human diseases. However, only a small number of lncRNAs were screened and characterized. Here, we identified 15 lncRNAs, which are associated with fatty liver disease. Among them, APOA4-AS is shown to be a concordant regulator of Apolipoprotein A-IV (APOA4) expression. APOA4-AS has a similar expression pattern with...

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PMID: 27131369
DOI: 10.1093/nar/gkw341

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