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Article

Biomarkers in the Management of Difficult Asthma.

Current topics in medicinal chemistry - 1 Jan 2016

Schleich Florence, Demarche Sophie, Louis Renaud

Abstract excerpt

Difficult asthma is a heterogeneous disease of the airways including various types of bronchial inflammation and various degrees of airway remodeling. Therapeutic response of severe asthmatics can be predicted by the use of biomarkers of Type2-high or Type2-low inflammation. Based on sputum cell analysis, four inflammatory phenotypes have been described. As induced sputum is timeconsuming and expensive technique,...

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Identifiers

PMID: 26467509
DOI: 10.2174/1568026616666151015093406
PMCID: PMC4997932

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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