Article
Comparative Analyses of the Relative Effects of Various Mutations in Major Histocompatibility Complex I-a Way to Predict Protein-Protein Interactions.
Applied biochemistry and biotechnology - 1 Sept 2016
Ali Ananya, Biswas Ria, Bhattacharjee Sanchari, Nath Prabahan, Pan Sumanjit, Bagchi Angshuman
Abstract excerpt
Protein-protein interactions (PPIs) play pivotal roles in most of the biological processes. PPI dysfunctions are therefore associated with disease situations. Mutations often lead to PPI dysfunctions, but there are certain other types of mutations which do not cause any appreciable abnormalities. This second type of mutations is called polymorphic mutations. So far, there are many studies that deal with the...
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