Impact of ACE2 gene polymorphism on antihypertensive efficacy of ACE inhibitors.

doi:10.1038/jhh.2016.24

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Article

Impact of ACE2 gene polymorphism on antihypertensive efficacy of ACE inhibitors.

Journal of human hypertension - 1 Dec 2016

Chen Y Y, Liu D, Zhang P, Zhong J C, Zhang C J, Wu S L, Zhang Y Q, Liu G Z, He M, Jin L J, Yu H M

Abstract excerpt

Angiotensin-converting enzyme 2 (ACE2), a newly discovered member of renin-angiotensin-aldosterone system, counterbalances the actions of angiotensin-converting enzyme. The objective of our study was to assess the association between rs2106809 polymorphism in ACE2 gene and the blood pressure response to ACE inhibitors in untreated hypertensive patients. After a 2-week, double-blind placebo run-in period, either...

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Identifiers

PMID: 27121444
DOI: 10.1038/jhh.2016.24

Genes

ACE2
ACE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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