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Article

Next-generation sequencing analysis of DUOX2 in 192 Chinese subclinical congenital hypothyroidism (SCH) and CH patients.

Clinica chimica acta; international journal of clinical chemistry - 1 Jul 2016

Fu Chunyun, Luo Shiyu, Zhang Shujie, Wang Jin, Zheng Haiyang, Yang Qi, Xie Bobo, Hu Xuyun, Fan Xin, Luo Jingsi, Chen Rongyu, Su Jiasun, Shen Yiping, Gu Xuefan, Chen Shaoke

Abstract excerpt

BACKGROUND: Defects in the human dual oxidase 2 (DUOX2) gene are reported to be one of the major causes of congenital hypothyroidism (CH). This study was set to examine the DUOX2 mutation spectrum and prevalence among Chinese CH and subclinical congenital hypothyroidism (SCH) patients and to define the relationships between DUOX2 genotypes and clinical phenotypes. METHODS: Peripheral venous blood samples were...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 27108200
DOI: 10.1016/j.cca.2016.04.019

Genes

DUOX2

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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