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Article

Genotypes and phenotypes of congenital goitre and hypothyroidism caused by mutations in dual oxidase 2 genes.

Clinical endocrinology - 1 Sept 2014

Wang Fang, Lu Kunna, Yang Zhifeng, Zhang Shasha, Lu Wei, Zhang Liqin, Liu Shiguo, Yan Shengli

Abstract excerpt

OBJECTIVE: The aim of this study was to screen for DUOX2, TPO and TG mutations in Chinese patients with congenital hypothyroidism (CH) and goitre and to define the relationships between DUOX2 genotypes and clinical phenotypes. METHODS: Blood samples were collected from 67 patients with CH and goitre in Shandong Province, China. Genomic DNA was extracted from peripheral blood leucocytes. PCR and direct sequencing...

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Source

Identifiers

PMID: 24735383
DOI: 10.1111/cen.12469

Genes

DUOX2
TPO

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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