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Article

The genetic characteristics of congenital hypothyroidism in China by comprehensive screening of 21 candidate genes.

European journal of endocrinology - 1 Jun 2018

Sun Feng, Zhang Jun-Xiu, Yang Chang-Yi, Gao Guan-Qi, Zhu Wen-Bin, Han Bing, Zhang Le-Le, Wan Yue-Yue, Ye Xiao-Ping, Ma Yu-Ru, Zhang Man-Man, Yang Liu, Zhang Qian-Yue, Liu Wei, Guo Cui-Cui, Chen Gang, Zhao Shuang-Xia, Song Ke-Yi, Song Huai-Dong

Abstract excerpt

OBJECTIVE: Congenital hypothyroidism (CH), the most common neonatal metabolic disorder, is characterized by impaired neurodevelopment. Although several candidate genes have been associated with CH, comprehensive screening of causative genes has been limited. DESIGN AND METHODS: One hundred ten patients with primary CH were recruited in this study. All exons and exon-intron boundaries of 21 candidate genes for CH...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 29650690
DOI: 10.1530/EJE-17-1017
PMCID: PMC5958289

Genes

DUOX2
DUOXA2
TPO
DUOXA1
FOXE1
HHEX
PAX8
TSHR

Provenance

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